Imaging Neuronal Dynamics at Single Spine Level
In 2017, the team led by Dr. Heping Cheng, the experienced academician of China Scientific Academy, successfully developed a miniature head-mounted two-photon microscope, which allowed animals to move around while “wearing” it. This new microscope has enabled, for the first time in the world, clear and stable imaging of neurons and synapses in the brain of free-moving mice. It is hailed as a revolutionary new tool for neuroscience.
In vivo Two-photon Microscopy Imaging System
The two-photon microscopy uses an microscope objective to focus near-infrared femtosecond laser pulses into the sample, where the fluorescence molecules at the focal point undergo two-photon absorption and emit fluorescence photons when returning from the excitated state to the ground state.
The imaging system manipulates the laser beam to perform three-dimensional scanning of the sample and records the spectral and intensity information of the light signal collected at each pixel position, thereby achieving multi-channel 3D tomography.
Honors & Patents
Possess multiple patents and awards
Apply for 36 patents, and the company has cooperated with multiple research institutions and hospitals
Published 56 articles in international conferences and journals, highly recognized by renowned experts and scholars in the industry
We have established business coperation with more than 50 domestic and foreign partners to achieve outstanding win-win results in global technology